The complexity of the hormonal effects of the diet is often overlooked as their levels change with macronutrient ratio at every meal. The amount of protein in a meal determines the levels of the hormone glucagon that helps to increase blood sugar levels. The levels and rate of entry of glucose in a meal determines the levels of the hormone insulin. It the balance of insulin and glucagon that stabilizes blood sugar levels. Finally, the level of omega-6 and omega-3 fatty acids in the diet determines the levels of eicosanoids or resolvins that can be generated. The ongoing dynamic balance of insulin to glucagon controls the generation of both eicosanoids and resolvins.