Obesity is the accumulation of excess body fat. The underlying cause is increased inflammation in the hypothalamus in the brain that distorts the sensitive energy-balance system that controls both the intake and metabolic use of incoming calories. The inflammation can come from either the diet or via metabolic endotoxemia going directly from the gut to the brain. Currently 36% of the U.S. adult population is obese.

The only way to treat obesity is the consumption of fewer calories without compromising the intake of essential nutrients while simultaneously reducing insulin and leptin resistance in the brain as well as other insulin-sensitive organs.