Dr. Barry Sears Dr. Sears Comments:

Another way to modulate auto-immune diseases like MS is to reduce the AA/EPA ratio with high-dose fish oil.  It will also normalize hormonal fluctuations.

Dr. Barry Sears Dr. Sears Comments:

Whatever happened to double-blind, placebo-controlled trials that are the basis of evidence-based medicine.  Comparing two relatively weak drugs without including a placebo arm for both is pathetic research.

 

Dr. Barry Sears Dr. Sears Comments:

This data has been known since 2000.  It is not the fish-oil dose per se, but the reduction of the AA/EPA ratio in the blood that has the benefits.  Ideally, the AA/EPA ratio should be about 1.5.  For most Americans, it will take about 7.5 grams of EPA and DHA per day to reduce their AA/EPA ratio (currently the average is 18) to that level.

Dr. Barry Sears Dr. Sears Comments:

I believe that published data would strongly suggest not taking statins for any type of MS.  This is why cardiologists love statins and neurologists hate them as the brain requires adequate levels of cholesterol for optimal function.

 

 

Dr. Barry Sears Dr. Sears Comments:

Progressive MS is caused by ongoing neuroinflammation.  The best way to cross the blood brain barrier and reduce neuroinflammation is high-dose fish oil.

 

Dr. Barry Sears Dr. Sears Comments:

There is also no barrier to the entry of anti-inflammatory omega-3 fatty acids into the brain that will also reduce neuroinflammation.

Dr. Barry Sears Dr. Sears Comments:

It’s nice to see the popular press jumping on the anti-inflammatory bandwagon, but it would nice if they understood anything about inflammation. If they did, they would put forward a balance of foods that can scientifically show the reduction of inflammation.

Dr. Barry Sears Dr. Sears Comments:

As usual the answer to MS lies with controlling inflammation.  Disturbances in the gut microbial composition is just one of the factors that leads to increased systematic inflammation.

 

Dr. Barry Sears Dr. Sears Comments:

Lost in the article is the fact that MS is a neuroinflammatory disease and that an anti-inflammatory diet rich in omega-3 fatty acids can reduce neuroinflammation.

 

Dr. Barry Sears Dr. Sears Comments:

Rather than using beta interferon to treat MS (which doesn’t do a very good job anyway), it makes more sense to reduce neuroinflammation with high-dose fish oil.