I am continually amazed how an inconsequential product like krill oil that is very low in EPA and DHA continues to get press headlines. The real take-home message of this article is that fish stocks for omega-3 fatty acids are decreasing. A recent article indicated that if all fish oil was used only for human consumption, then there would only be enough fish oil for 6% of world population to obtain the same levels of EPA and DHA as found in the Japanese population. Soon we will have two populations; one with adequate levels of EPA and DHA and those that don’t. This will generate cognitive and inflammatory control inequality.
I think I have been saying that since 2002 when I wrote The OmegaRx Zone. Of course this is true only if you are taking adequate levels of EPA and DHA to generate the hormones (irritable) that resolve chronic inflammation.
I certainly hope that he is studying the use of high-dose omega-3 fatty acids to increase resolvin production. You don’t need to go to graduate school to read that literature and begin to practice its use.
For one aspiring cognitive scientist at the University of Texas at Dallas, the prospect of treating veterans suffering from traumatic brain injury hits close to home- Morgan Luttrell, 40, was deployed nine times to Iraq and Afghanistan as a Navy SEAL, and he has suffered brain trauma himself.
I will have a more complete blog on this next week, but what they consider a “high” dose is essentially “just beyond a placebo” dose. The reduction in the scarring of the heart was due to increased resolvin formation that requires high levels of omega-3 fatty acids in the blood. This is why lower dose studies were inconclusive because they were using placebo doses.
Many heart doctor will tell you that one of the best ways to keep your heart healthy is to include more healthy oils, such as omega-3 fatty acids found in fish, in your diet.
The reason the answer isn’t clear is because the studies have had their subjects taking placebo doses of omega-3 fatty acids. The secret of omega-3 fatty acids is that they are substrates for hormones (resolvins) needed to resolve existing inflammation. Until you get the AA/EPA ratio under 3, then you are not going to see any benefit of omega-3 fatty acids. The average AA/EPA ratio for Japanese is 1.5 to 3 compared to the average American who has an AA/EPA ratio of 18. To get the same AA/EPA ratio as the Japanese will require about 5 to 7.5 grams of EPA and DHA per day.
Omega-3s are the fats that made fish famous. Really famous: fish oil is now the most popular natural product in America among U.S. adults-8% of whom take it-and children. Our bodies need these essential unsaturated fats but can’t produce them, so we rely on sources like seafood or supplements to get enough.
The best hope for regenerative medicine is the increased production of resolvins to cause regeneration of existing tissue. All you need to reach that goal is to take a lot of omega-3 fatty acids.
Four years ago, Shinya Yamanaka received a phone call that would forever change his destiny. The Kyoto University professor had won a Nobel Prize for his work in stem cell biology, which has since sparked a torrent of investment into regenerative medicine in Japan, a fast-moving field the country’s pharmaceutical industry aims to dominate.
A far more powerful study based on actual blood chemistry can be found at Sekikawa et al. Prostaglandins Leukotrienes Essential Fatty Acids 87:11 (2012) or you can read about in my blog at http://www.zonediet.com/
This is a surprisingly good article for the general public on the importance of omega-3 fatty acids. That’s why my minimum recommended intake is 2.5 grams of EPA and DHA per day. That’s 10 times more than the government recommendation and 20 times more than the average daily intake for Americans. For comparison, however, that 2.5 grams is the same amount that your great grandparents gave your grandparents when they had to consume a tablespoon of cod liver oil every day.
When news broke earlier this year ABC had cut the cord on their soapy Music City drama, the internet exploded into mayhem. While the season
The title of the article should have been “Why Fish Oil Supplements Probably Won’t Help Unless You Reduce Your AA/EPA Ratio To The Level Of The Japanese Population.” In other words, you have to take enough to make a difference.
This article neglects to mention that when you bring the AA/EPA ratio to Europeans to the same levels as the Inuit, you see the same metabolic changes and benefits.
Some people, for example, are able to digest milk throughout their lives. This genetic adaptation arose in societies that domesticated cattle thousands of years ago, in such places as Northern Europe and East Africa. People who trace their ancestry to other regions, by contrast, tend to more often be lactose-intolerant.