Dr. Barry Sears Dr. Sears Comments:

This indicates the powerful benefits of high-dose EPA and DHA when given at a therapeutic dose.  As mentioned in the article, the benefits in the animal models translates into 6-12 grams of EPA and DHA per day in humans.  That has been my contention since I published my book, The OmegaRx Zone, in 2002.  You need a therapeutic dose to get a therapeutic effect.

Omega-3 oil may stop the onset of lupus: Study

Consuming an omega-3 fatty acid could halt an episode of lupus and possibly the trigger of other autoimmune conditions, a mouse study has found. The research investigated the influence of various concentrations of docosahexaenoic acid (DHA) – an omega-3 fatty oil – on lung and kidney lesions caused by the autoimmune condition lupus.

Dr. Barry Sears Dr. Sears Comments:

The data is very clear that if you dramatically increase the omega-3 and simultaneously decrease the omega-6 fatty acids, the resulting decrease in the AA/EPA ratio in the blood correlates very strongly with improved learning and behavior.

Omega-3, Omega-6 Fatty Acids Enhance Reading Skills In Children, Study Says

First Posted: Sep 21, 2016 03:00 AM EDT Researchers discovered that there are positive effects of omega-3 and omega-6 fatty acids in children with inattention and reading difficulties. The intake of fatty acids could improve their reading skills. The study was printed in the Journal of Child Psychology and Psychiatry.

Dr. Barry Sears Dr. Sears Comments:

This is why  omega-3 fatty acids are called “brain food”.  More than 20% of the dry mass of the brain is composed of omega-3 fatty acids that highly concentrated in the synaptic regions of the nerves.  Without adequate levels of omega-3 fatty acids in the diet, nerve transmission is highly compromised.

Eating Fish Preserves Your Memory, Says Study

Worried that your memory is deserting you? Some scientists think the solution is sitting on ice at the grocery store. A new study published in the journal Neurology suggests that just one serving of seafood a week could help prevent age-related memory loss, due to its high omega-3 fatty acid content.


Dr. Barry Sears Dr. Sears Comments:

The only fatty acids associated with increased risk were DPA and AA.  DPA is a minor omega-3 fatty acid and AA is found in red meal and other animal sources of protein.  Bottom line is eat low-fat protein and supplement the diet with fish oil that is rich in EPA and DHA and low in DPA, which is virtually all fish oil products except for menhaden that is rich in DPA.  Menhaden is primarily used as fish meal to feed beef.

Certain Fatty Acids Increased Risk for Type 2 Diabetes in Women

High intake of certain fatty acids increased type 2 diabetes risk in women. Women who consumed high amounts of total omega-3 polyunsaturated fatty acids (PUFAs) were at increased risk for developing type 2 diabetes, regardless of BMI, according to new research.

Dr. Barry Sears Dr. Sears Comments:

I am continually amazed how an inconsequential product like krill oil that is very low in EPA and DHA continues to get press headlines.  The real take-home message of this article is that fish stocks for omega-3 fatty acids are decreasing.  A recent article indicated that if all fish oil was used only for human consumption, then there would only be enough fish oil for 6% of world population to obtain the same levels of EPA and DHA as found in the Japanese population.  Soon we will have two populations; one with adequate levels of EPA and DHA and those that don’t.  This will generate cognitive and inflammatory control inequality.

Dr. Barry Sears Dr. Sears Comments:

I think I have been saying that since 2002 when I wrote The OmegaRx Zone.  Of course this is true only if you are taking adequate levels of EPA and DHA to generate the hormones (irritable) that resolve chronic inflammation.




Dr. Barry Sears Dr. Sears Comments:

If you have brain fog, you need a little more structure than given in this article.  Most of the foods mentioned are fine if they are used in the context of a balanced anti-inflammatory diet.  If you really want to get rid of brain fog, then reduce your AA/EPA ratio to between 1.5 and 3 and stabilize blood sugar by keeping your HbA1c around 5.0%.


11 Foods To Eat If You Experience Brain Fog, So You Can Be More Focused & Alert

When you have trouble concentrating or remembering things, you might not think to blame your diet for that constant haziness that’s clouding your mind. However, food plays a role in your cognitive functioning, and there are certain foods to eat that can help clear up your brain fog.


Dr. Barry Sears Dr. Sears Comments:

I certainly hope that he is studying the use of high-dose omega-3 fatty acids to increase resolvin production.  You don’t need to go to graduate school to read that literature and begin to practice its use.

Navy SEAL vet becomes scientist to study brain diseases | Fox News

For one aspiring cognitive scientist at the University of Texas at Dallas, the prospect of treating veterans suffering from traumatic brain injury hits close to home- Morgan Luttrell, 40, was deployed nine times to Iraq and Afghanistan as a Navy SEAL, and he has suffered brain trauma himself.



Dr. Barry Sears Dr. Sears Comments:

I will have a more complete blog on this next week, but what they consider a “high” dose is essentially “just beyond a placebo” dose.  The reduction in the scarring of the heart was due to increased resolvin formation that requires high levels of omega-3 fatty acids in the blood.  This is why lower dose studies were inconclusive because they were using placebo doses.


Fish Oil Has Benefits After a Heart Attack: Study

Many heart doctor will tell you that one of the best ways to keep your heart healthy is to include more healthy oils, such as omega-3 fatty acids found in fish, in your diet.



Dr. Barry Sears Dr. Sears Comments:

The reason the answer isn’t clear is because the studies have had their subjects taking placebo doses of omega-3 fatty acids.  The secret of omega-3 fatty acids is that they are substrates for hormones (resolvins) needed to resolve existing inflammation.  Until you get the AA/EPA ratio under 3, then you are not going to see any benefit of omega-3 fatty acids.  The average AA/EPA ratio for Japanese is 1.5 to 3 compared to the average American who has an AA/EPA ratio of 18.  To get the same AA/EPA ratio as the Japanese will require about 5 to 7.5 grams of EPA and DHA per day.

Fish Oil Is Hugely Popular-But Should You Take It?

Omega-3s are the fats that made fish famous. Really famous: fish oil is now the most popular natural product in America among U.S. adults-8% of whom take it-and children. Our bodies need these essential unsaturated fats but can’t produce them, so we rely on sources like seafood or supplements to get enough.