Dr. Barry Sears Dr. Sears Comments:

An increase in ceramide is also a major factor in the development of insulin resistance.  The primary fatty acid in ceramide is palmitic acid.  Therefore one of the best ways of reducing insulin resistance in every tissue is to reduce the dietary intake of palmitic acid, which is the primary fatty acid in saturated fat.

http://www.medicaldaily.com/brain-disease-risk-lowered-fat-protects-against-parkinsons-and-alzheimers-397672