Dr. Barry Sears Dr. Sears Comments:

You have to read this article very carefully to find that there is a linkage between saturated fat and heart disease when the glycemic load of the diet is reduced.  That’s why monounsaturated fats are superior to saturated fats.  The reason is that saturated fat (especially palmitic acid) causes inflammation in the hypothalamus that increases hunger.  Monounsaturated fats have the opposite effect.  This is why a Mediterranean diet (rich in monounsaturated fat) is superior to a high-saturated-fat diet in terms of heart disease.  The logical extension is the Mediterranean Zone Diet, which is even more heart healthy than the traditional Mediterranean diet  because it is also a stricter anti-inflammatory diet.