Dr. Barry Sears Dr. Sears Comments:

The problem with resveratrol is that it is very water insoluble, meaning very little gets into the blood even at 4 grams per day.  On the other hand, maqui polyphenol extracts are much more water-soluble; and therefore, more get into the blood and ultimately into the brain. However, polyphenols will not resolve neuroinflammation that characterizes Alzheimer’s, but high-dose omega-3 fatty acids will.  I believe the drug of the future for treating and preventing Alzheimer’s will be a combination of high-dose omega-3s and high-dose maqui polyphenols.