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For diabetes in obesity, weight-loss surgery beats medication

(Reuters Health) - Weight-loss surgery beats medication for controlling type 2 diabetes in obese people, according to the longest-term trial ever to compare the two approaches. Half of the patients treated with weight-loss surgery in the study were diabetes-free at five years, said Dr. Francesco Rubino of Kings College London in the UK and colleagues in a report in The Lancet.

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Dr. Sears Comments:

Dr. Barry Sears

The primary reasons why gastric bypass surgery does better is because it increases the release of PYY from the gut to cause satiety while simultaneously decreasing the release of ghrelin from the stomach that induces hunger.  If you aren’t hungry due to improved hormonal balance in the gut, your caloric intake decreases more than through willpower alone.


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