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Intestinal Gel Improves Non-Motor Symptoms in Parkinson’s

SAN DIEGO -- A levodopa/carbidopa gel (Duopa) that gets delivered directly to the gut diminished non-motor symptoms in Parkinson's disease, researchers reported here. In an interim analysis of an open-label study, patients had significant improvement in the Non-Motor Symptom Scale (NMSS) from baseline, David Standaert, MD, of the University of Alabama at Birmingham, reported during a poster session at the Movement Disorders Society meeting here.

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Dr. Sears Comments:

Dr. Barry Sears

More than half the dopamine in the body is made in the gut by bacteria.  Getting a better microbial balance in the gut may be more useful than a new drug-delivery system for dopamine.

 

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