Dr. Barry Sears Dr. Sears Comments:

When I was doing cardiovascular research in the mid-1970s, the best way to induce a new lesion in chimpanzees was to do a balloon angioplasty in a normal artery because the inflammation it induced would quickly create an atherosclerotic lesion.  Somehow it was thought if you put a steel bridge to support the inflamed artery, then you would be OK.  Maybe that’s why about 1/3 of stents fail today because the inflammation is still being induced and eventually overwhelms the steel bridge.