Dr. Barry Sears Dr. Sears Comments:

There are two factors that have nothing to do with genetics that are more important in developing depression.  One is a deficiency of omega-3 fatty acids (especially EPA). The other is inflammation induced by gut microbes that are directly transmitted to the brain via the vagus nerve to increase neuroinflammation.

 

New insights into genes affecting depression risk

In a key advance for the study of depression, a comprehensive scan of human DNA has turned up the apparent hiding places of more than a dozen genes linked to the disorder. “This is a jumping-off point” for further work to reveal the biological underpinnings of depression, which in turn can guide development of new drugs, said Ashley Winslow, an author of a paper on the work.