Dr. Barry Sears Dr. Sears Comments:

One of the secrets of high-dose polyphenols is their activation of AMP kinase.  However, they have to get into the blood to do that.  This is why delphinidins are about 400 times more potent than resveratrol.  The delphinidins in tissue culture are better activators of AMP kinase than resveratrol, and they are far better absorbed than resveratrol.