Dr. Barry Sears Dr. Sears Comments:

This data has been known since 2000.  It is not the fish-oil dose per se, but the reduction of the AA/EPA ratio in the blood that has the benefits.  Ideally, the AA/EPA ratio should be about 1.5.  For most Americans, it will take about 7.5 grams of EPA and DHA per day to reduce their AA/EPA ratio (currently the average is 18) to that level.