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Study Suggests Blood-Brain Barrier Leaks Associated With Alzheimer’s Disease

First Posted: Jun 06, 2016 04:00 AM EDT The brains of patients in the early phases of Alzheimer's disease may likely have more "leaks" in barriers that separate it from the bloodstream. According to a study published in the journal Radiology, the so-called "blood-brain barrier" has tightly joined cells which mark the brain's blood vessels.

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Dr. Sears Comments:

Dr. Barry Sears

This is in line with new data that indicates amyloid plaques may be the result if microbial invasion into the blood via a leaky blood-brain-barrier just like microbes can leak into the bloodstream via a leaky gut barrier.  The primary agents that causes both barriers to become more permeable is increased inflammation, and in particular an increase in leukotrienes derived from arachidonic acid.

 

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