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Sugar’s ‘sweet spot’ link to Alzheimer’s disease discovered

The findings appear to centre on the damage high blood sugar levels does to a key enzyme in the inflammatory response in the condition's early stages. High blood sugar levels or hyperglycaemia is one of the hallmarks of diabetes as well as obesity and potentially places those with these conditions at a heightened risk of brain complications.

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Dr. Sears Comments:

Dr. Barry Sears
The best way to reduce excess glycation of proteins is the reduction of oxidative stress.  Both metformin and polyphenols employ the same mechanism by activating the SIRT-1 gene that increases the expression of AMP kinase.

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