Dr. Barry Sears Dr. Sears Comments:

It is only the ApoE4 gene variant that is related to Alzheimer’s. It appears that this gene variant decreases the transport of DHA into the brain (Vandal M et al. “Reduction in DHA transport to the brain of mice expressing human APOE4 compared to APOE2.” J Neurochem. 2014 May;129(3):516-26). Rather than blocking all ApoE actions, simply increase the dietary intake of DHA in those with ApoE4.