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The Latest About Antidepressants and Weight Gain. n

A common complaint among patients on antidepressants is that their drugs cause them to gain weight. It's not fully understood why this happens, or which are the worst offenders, but a new study published in the journal JAMA Psychiatry tried to figure it out by comparing a variety of drugs prescribed for anxiety and depression.

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Dr. Sears Comments:

Dr. Barry Sears

Bottom line is both anti-depressant use and quitting smoking cause weight gain. Anti-depressants affect the serotonin pathways; lack of smoking affects the dopamine pathways. I believe taking high-dose fish oil can overcome the side-effects of either action because the omega-3 fatty acids will improve both serotonin and dopamine efficacy.

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