There’s less science around fructose than you think. Carefully controlled studies have indicated when comparing isocaloric levels of fructose and glucose, there is no difference on weight gain, but that fructose does lower insulin levels relative to glucose. It’s excess insulin (caused by insulin resistance) that makes you fat and keeps you fat. The best way to increase insulin resistance is to follow a diet rich in grains and starches (both devoid of fructose) coupled with intakes of omega-6 fatty acids.
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