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Praluent Looks Cheap to Those With Extreme Cholesterol

Doctors say F.H. is more common than cystic fibrosis or Down syndrome, yet largely unrecognized. Only 1 percent to 10 percent of people with F.H. know they have it, often because doctors do not think of it when patients have high cholesterol.

Read the article on Nytimes

Dr. Sears Comments:

Dr. Barry Sears

When I was working on heart disease at Boston University, the FH patients were the really interesting ones to work with since you would often see cholesterol deposits on their skin and eyelids.  There is no question for this vey select group of patients that the new drug is very useful.  However, the same FH patients had very low rates of cancer.  I suspect when this drug gets wider population use  in patients other than those with FH, LDL will drop but there will be a significant increase in cancer after five years of use.



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